O'Reilly has said Armstrong trashed her after she spoke out publicly.
There are far more cases of Armstrong lashing out against those who crossed his path, such as journalist David Walsh, author of "L.A. Confidentiel -- Les Secrets de Lance Armstrong."
But let's turn to some of the former cycling legend's past claims about his record and where the alleged "witch hunt" came from.
"He's trying to back up his old lady."
Among those who crossed Armstrong's path was fellow cyclist Frankie Andreu. He and his wife, Betsy, were once among Armstrong's closest friends. The two say they were with Armstrong when he told a doctor he had taken performance-enhancing substances, including EPO, testosterone, cortisone, growth hormone and steroids. The Andreus testified about the incident under oath.
Armstrong, in a videotaped deposition, said he had never made such remarks. As for Frankie Andreu, Armstrong said, "I feel for him," adding, "I think he's trying to back up his old lady."
Sports Illustrated reported that Armstrong disparaged Betsy Andreu's testimony for years, "telling SI in 2007 that Andreu was motivated by 'bitterness, jealousy and hatred' and claiming to The Guardian (a British publication) a year later, 'Betsy blogs 24 hours a day about me. If that ain't sick, what is?'"
Betsy Andreu said she had to go on "a quest to clear my name because I never, ever, ever lied about anything."
Her remarks came in a documentary, first shown on Australian TV network ABC and later broadcast by CNN, in which Armstrong's remarks under oath can be seen.
500-600 drug tests...
Armstrong and his representatives have cited this figure repeatedly.
"Throughout his 20-plus year professional career, Mr. Armstrong has been subjected to 500 to 600 drug tests," one of the lawsuits his attorneys filed read.
But records show that he apparently has not had nearly that many, the USADA report said.
The USADA itself tested Armstrong fewer than 60 times, and the International Cycling Union tested him about 215 times, the USADA report said.
... and "not a single positive test"
The other half of that often repeated claim from Armstrong and his camp has obviously carried more weight: that there was not "a single positive test."
"Six samples that were taken from Lance Armstrong were retested in '05 and they were positive," USADA head Tygart recently told "60 Minutes."
The tests were originally taken in 1999, before there was a test for EPO, he said. When new tests were conducted in 2005, "all six were flaming positive," he said.
Also, as part of its investigation, USADA had test results from 38 blood samples, taken between 2009 and 2011, analyzed. The analyst found that samples taken during the 2009 and 2010 tours showed blood values whose likelihood "of occurring naturally was less than one in a million," and other indications of blood doping," the New York Times noted. USADA also outlined methods Armstrong and others used to circumvent the system, the Times reported.
"I'm doing it to fund the fight against doping"
A classic Armstrongism, captured on video at a deposition.
Armstrong was being asked about a $25,000 personal check he wrote to the International Cycling Union, cycling's governing body. He also pledged a further $100,000.
"For an athlete to be paying money to the people who police him is -- it's unconscionable," Dr. Michael Ashenden of the organization Science and Industry Against Blood Doping said in the documentary from Australian TV aired on CNN.
It's about international relations