Carney Hospital in Dorchester, Massachusetts, reported receiving four or five patients, none in serious condition.

Combined, that brings the number of injured to as many as 82. There are other hospitals in the Boston area as well.

The full number of casualties was not immediately known, Davis said.

Crowds were in the area watching the runners.

Map: Boston Marathon explosions

Two explosions have been reported near the Boston Marathon finish line on Boylston Street, with reports of injuries, according to WCVB-TV.

'Horrific day'

"This is a horrific day in Boston," Massachusetts Gov. Deval Patrick said in a statement.

"My thoughts and prayers are with those who have been injured. I have been in touch with the president, Mayor (Thomas) Menino and our public safety leaders. Our focus is on making sure that the area around Copley Square is safe and secured. I am asking everyone to stay away from Copley Square and let the first responders do their jobs."

U.S. Attorney General Eric Holder spoke with FBI Director Robert Mueller and U.S. Attorney Carmen Ortiz, a Justice Department official said.

Holder has directed the full resources of the Justice Department to be deployed to ensure the matter is fully investigated, the official said.

The Federal Aviation Administration placed a flight restriction over the site of the blasts.

Other cities, including New York and Washington, tightened security as a result. Following standard protocol, the White House cleared out an area in front of the West Wing.

"If you see something, say something," Mark Boughton, mayor of Danbury, Connecticut, wrote on Twitter. "All cities will be on a heightened state of alertness per Homeland Security protocols."

Mike Baingon, who works at the Atlantic Fish Company in Boston, said an explosion took place in front of the restaurant and that he was right by the front door at the time.

The explosions occurred at about 2:45 p.m., more than two hours after the first of the race's nearly 27,000 runners had crossed the finish line, CNN Producer Matt Frucci reported.

The race was halted as was subway service into the area.

Runners east of Massachusetts Avenue were directed to Boston Common; those west of Massachusetts Avenue were directed to Kenmore Square, the state's emergency management agency said.

Troops from the Massachusetts National Guard were assisting police as well.

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