A big rig driver lost control of his 18-wheeler on the northbound lanes of Interstate 37 near Brooklyn, causing it to jackknife early Friday morning.
A set of wheels on the cab dangled off the bridge when the 18-wheeler came to a stop at around 1:15 a.m.
Slick roads due to light rain might have been a factor in the crash, San Antonio police said.
All lanes of I-37 North were closed in the area as well as Austin Street.
The driver was not injured.
The highway reopened around 5 a.m.