Emergency room physician Donna Campbell has won the Republican nomination for state Senate District 25, defeating 19-year incumbent Sen. Jeff Wentworth.

Campbell has never held public office but finished a surprising second in the May 29 primary to force her way into Tuesday's runoff. A tea party favorite, Campbell was buoyed by attacks on Wentworth, who was targeted for defeat by business groups who called him too moderate.

Campbell ran for Congress in 2010 and moved to New Braunfels to take up residency in the district just before filing for the state Senate campaign. District 25 stretches from South Austin to San Antonio.