Fire broke out at a two story home in the 3400 block of Maitland Road at around 8:30 a.m.
The home, located on the far north side near Evans Road, was engulfed in flames when neighbors noticed.
"It was one of the most awe-striking things I've ever seen," said neighbor Dale Haines. "It was just a big ball of flames basically."
The danger didn't stop neighbors from rushing to help.
Haines, along with neighbors Derek Setser and off-duty firefighter Jesse Garcia, said they were concerned about the family of three, who had recently moved into the home.
"I wanted to make sure that A, nobody got hurt, and B, the fire doesn't spread to anybody else's house," said Setser.
"We knocked on the door (but) nobody opened the door. We finally knocked it down, broke the glass, unlocked the door and we started yelling in there, but there was no way we could go in there since it was full of smoke already," said Garcia.
Neighbors used fire extinguishers and water hoses to try to keep the fire from spreading until firefighters arrived.
When they got to the scene, firefighters immediately swept the home, looking for victims.
It turned out nobody was home.
Firefighters said the home sustained about $150,000 in damage.
The home next door also had some minor damage but homeowner Valerie Finley said it could have been a lot worse.
"If it hadn't been for our wonderful neighbors who got the hoses on the house, who knows how bad the damage would have been," she said.
Arson investigators are looking into the cause of the fire. They believe it started on the deck.