Chase White, 25, was riding his bicycle home from work Tuesday night in the 4000 block of Broadway when the driver of an SUV hit him from behind, San Antonio police said.
EMS transported White to an area hospital, and he was expected to recover.
Police said White had lights illuminated on the front and back of his bicycle and he was wearing a helmet.
With more people commuting on two wheels, Julia Murphy, special projects manager for San Antonio's Sustainable Transportation Department, said everyone needs a reminder to look out for cyclists.
"San Antonio wants to be tolerant of all the users of our roadways. That includes cyclists and pedestrians, as well as motorists," she said.
Pete Esquivel spends hours on his bike every day and said he has been cut off by drivers more than once.
"It was a green light, and I was coming up, didn't have a turn signal. (The driver) turned right in front of me. I went flying over the hood (and the driver) didn't even stop," he said.
But Esquivel and Murphy were also quick to point out that cyclists are often to blame for conflict between drivers and cyclists.
"They just go straight through red lights, stuff like that, or they don't wear helmets. It's like they don't have a concern for safety," Esquivel said.
Murphy is encouraging more people to push pedals around San Antonio, but she's also pushing for having lights, wearing reflective clothing and having an awareness of cars.
She said there is enough road to go around if everyone does their part to share.