EXPLAINER: Why it's hard to make vaccines and boost supplies
FILE - In this Friday, Jan. 22, 2021 file photo, empty vials of the Pfizer-BioNTech COVID-19 vaccine are seen at a vaccination center at the University of Nevada, Las Vegas in Las Vegas. (AP Photo/John Locher)With demand for COVID-19 vaccines outpacing the world’s supplies, a frustrated public and policymakers want to know: How can we get more? Makers of COVID-19 vaccines need everything to go right as they scale up production to hundreds of millions of doses — and any little hiccup could cause a delay. “It’s just not that easy.”DIFFERENT VACCINES, DIFFERENT RECIPESThe multiple types of COVID-19 vaccines being used in different countries all train the body to recognize the new coronavirus, mostly the spike protein that coats it. But possibly the easiest way to get more doses is if other vaccines in the pipeline are proven to work.
Some COVID-19 mutations may dampen vaccine effectiveness
Researchers expressed concern Wednesday about the preliminary findings, in large part because they suggest that future mutations could undermine vaccines. One way vaccines work is to prompt the immune system to make antibodies that block the virus from infecting cells. The Rockefeller researchers got blood samples from 20 people who had received either the Moderna or Pfizer vaccine and tested their antibodies against various virus mutations in the lab. The slower we roll out vaccine around the world, the more opportunities we give this virus to escape” and develop mutations, he said. Moderna and AstraZeneca, which makes a different type of COVID-19 vaccine used in some countries, also have been testing how their vaccines hold up against different mutations.
Years of research laid groundwork for speedy COVID-19 shots
How could scientists race out COVID-19 vaccines so fast without cutting corners? A head start helped -- over a decade of behind-the-scenes research that had new vaccine technology poised for a challenge just as the coronavirus erupted. Both shots -- one made by Pfizer and BioNTech, the other by Moderna and the National Institutes of Health -- are so-called messenger RNA, or mRNA, vaccines, a brand-new technology. U.S. regulators are set to decide this month whether to allow emergency use, paving the way for rationed shots that will start with health workers and nursing home residents. Traditionally, making vaccines required growing viruses or pieces of viruses — often in giant vats of cells or, like most flu shots, in chicken eggs — and then purifying them before next steps in brewing shots.
Summer may decide fate of lead shots in virus vaccine race
Many scientists dont expect a coronavirus vaccine to be nearly as protective as the measles shot. If the best COVID-19 vaccine is only 50% effective, "thats still to me a great vaccine, said Dr. Drew Weissman of the University of Pennsylvania. About 15 experimental COVID-19 vaccines are in various stages of human studies worldwide. Nothing is going to be easy.The Oxford shot, with a 10,000-person study underway in England, already encountered that hurdle. EXPECT IMPERFECT PROTECTIONAnimal research suggests COVID-19 vaccines could prevent serious disease but may not completely block infection.
'The Masked Singer': The Skeleton Gets Buried -- See Who Was Under the Sparkly Skull Mask!
*The field of costumed contestants is getting even narrower following the fourth week of competition on The Masked Singer. "I was with him just last week," Shaffer told Jeong. The Masked Singer airs Wednesdays at 8 p.m. ET/PT on Fox. Dr. Drew Spills 'Masked Singer' Secrets! How Contestants Keep Their Identities Under Wraps Embed Code RestartRELATED CONTENT:Jenny McCarthy Has Guessed 'a Lot' of 'Masked Singer' Identities: How the Show Avoids Spoilers (Exclusive)Mariah Carey Addresses Rumors She's on 'The Masked Singer'
Dr. Drew Reveals Intense Security Measures Behind Keeping His 'Masked Singer' Secret
After donning a massive eagle costume and belting out Meatloaf, Dr. Drew Pinsky was unmasked and became the latest celeb to get sent home on Wednesday's The Masked Singer. "Then, I put that damn eagle costume on, and I was like, 'Oh no, it's a rock eagle, we have to go a totally different direction!' The Masked Singer airs Wednesdays at 8 p.m. ET/PT on Fox. 'The Masked Singer' Episode 3: Reveals, Theories and New Clues! Embed Code RestartRELATED CONTENT:'The Masked Singer': Week 3 Brings Brand New Clues, Epic Performances and a Surprising Celeb Reveal'The Masked Singer': Eagle Sent Soaring Home -- See Who's Under the Mask!
'The Masked Singer': The Eagle Sent Soaring Home After Exciting Week 3 -- See Who Was
*The competition is heating up and the mystery is getting even more thrilling after Week 3 of The Masked Singer! The show brought Group D to the stage, which saw The Eagle, The Flower, The Penguin and The Fox all duke it out with their different performances. After the audience votes were tallied, The Penguin emerged victorious, sending The Eagle to the chopping block. Laila Ali Says Her 'Mom Cool Factor' Is Much Higher After 'The Masked Singer' Embed Code RestartRELATED CONTENT:'The Masked Singer': ET Will Be Live Blogging Week 3! 'The Masked Singer': Our Best Guesses at the Secret Identities'The Masked Singer': The Most Stunning Performances, Revealing Clues and Shocking Twists of Week 2!
Amber Portwood Denies Attacking Ex and Son With Machete in First Interview Since Arrest
Amber Portwood is telling her side of the story -- well, as much of it as she can. At the time, Andrew claimed that Amber came at him and their 1-year-old son, James, with a machete. On Tuesday nights part two of the Teen Mom OG reunion, Dr. Drew Pinsky traveled to Indiana to interview Amber about the season and the alleged incident. Shes very sweet, very sweet person.She also claimed the machete incident completely ripped my heart out." During the reunion, Amber mostly avoided sharing details about the alleged incident, but insisted that the machete story was entirely false.