Bryce Miller gave up two hits over six shutout innings for his first major league win, Justin Topa worked around a leadoff single in the ninth for his first big league save and the Seattle Mariners beat the Houston Astros 3-1 to take two of three from the World Series champions.

Ian Happ had three hits, including a tiebreaking two-run double in the seventh inning, and the Chicago Cubs beat the Milwaukee Brewers 5-4 on opening day.

Jace Peterson hit a go-ahead single in the seventh, Lorenzo Cain homered for a second straight game and the Milwaukee Brewers knocked the San Francisco Giants out of the top spot in the National League for the first time in more than three months.

Milwaukee right-hander Corbin Burnes struck out 10 consecutive batters, tying the major league record and leading the Brewers past the Chicago Cubs 10-0.

Nolan Arenado hit a tiebreaking, two-run homer in the eighth inning of his home debut with the Cardinals, lifting St. Louis over the Milwaukee Brewers 3-1 as fans returned to Busch Stadium for the first time since 2019.